Intestinal disorders: Irritable Bowel Syndrome (IBS), Ulcerative Colitis, The Relationship between Crohn's Disease and Bile

intestinal disease, IBS, colitis ulcerosa, SIBO, Crohn disease

Irritable bowel syndrome (IBS)

‘Irritable Bowel Syndrome, or IBS, is a chronic problem that affects the digestive system and its functions. The rise in IBS symptoms could be link to a number of complex reasons. Important factors to consider, which may lead to and maintain the symptoms of IBS, are dietary and genetic factors, psychological dysfunction, hormonal imbalance and infection and inflammation. It is often noted by patients that stress exacerbates their IBS symptoms. However the cause of IBS still remains unclear’ Source:


‘Crohn’s disease is a lifelong inflammatory bowel disease. It can trigger inflammation in any part of your digestive system, causing tummy pain, persistent diarrhoea and ulcers. It can also make you feel more tired than usual and lose weight.’ Source:

Crohn’s disease is diagnosed in about 1 in 10,000 people every year. About 145 in every 100,000 people in the UK have Crohn’s disease. Source:

Colitis ulcerosa

‘The colon is the large intestine, or bowel, and the rectum is the end of the bowel where stools are stored. Ulcers can develop on the colon’s lining and bleed and produce pus.
Ulcerative colitis is a form of colitis that is caused by autoimmune inflammation (the body attacking itself), whereas colitis can be caused by a number of factors including infection.
Ulcerative colitis is similar to another condition which causes inflammation of the gut – Crohn’s disease.’ Source:

‘Ulcerative colitis is the most common type of inflammatory disease of the bowel. It has an incidence in the UK of approximately 240 per 100,000.’

Contaminated small bowel syndrome - SIBO

‘Small Intestinal Bacterial Overgrowth (SIBO) is a disease that mainly affects the digestive tract. SIBO, as the English term implies, is an overgrowth of intestinal bacteria in the small intestine. If, for some reason, the small intestine becomes overpopulated with bacteria from the large intestine (and contaminated), unpleasant symptoms such as bloating, increased gas production, abdominal cramps, alternating diarrhoea and constipation occur.’ Source:

What is the role of bile acids and bile in the above bowel diseases?

If there is a problem with the breakdown of fats (e.g. for gall bladder surgery), then fat digestion will occur through a putrefaction process, which will spoil the bacterial flora in the colon. This disruption allows previously unknown microorganisms to colonise and multiply in the intestines. This can trigger inflammatory processes, which can lead to pain and cramping.

The proper liver function, bile production, bile circulation (enterohepatic circulation) can prevent the listed intestinal diseases. If the bile cycle is not functioning properly or is damaged for any reason, bile acid supplementation can help to alleviate the symptoms of these diseases and speed up recovery, as bile acids support the bile cycles, the digestion, gut and immune health, are involved in alleviating your disturbances.

Over the past 10 years of marketing, we have received a lot of positive feedback on the use of the product for IBS, but not for everyone, particularly those with constipation symptoms.

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